An in vitro test of new peptide against melanoma
Experimental Oncology Unit, Department of Microbiology, Immunology and Parasitology, Federal University of São Paulo, São Paulo, SP, Brazil.
Research Article
World Journal of Advanced Research and Reviews, 2022, 14(01), 024–028
Article DOI: 10.30574/wjarr.2022.14.1.0260
Publication history:
Received on 18 February 2022; revised on 26 March 2022; accepted on 28 March 2022
Abstract:
Peptides have fantastic functions like prions pathogens that cause transmissible diseases devoid of nucleic acid. Furthermore, because of their high specificity, peptides can be used in antitumor therapy to target specific targets. In this work we describe the in vitro antitumor action against B16F10 cells of a peptide named W12K obtained from immunoglobulin gene. As a result, we showed antitumor growing in experimental trials such as viability, migration, and cell cycle. In conclusion the present article describes a molecule from immunoglobulin with future potential for in vivo therapeutic test.
Keywords:
Peptide; Antitumor Activity; Cell Cycle; B16F10 Melanoma; Aggressive Tumor Cells; Cell Migration
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Copyright © 2022 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0