Department of Medical Oncology, Oncology Hospital, Hassan II University Hospital, Faculty of Medicine, Pharmacy and Dentistry, Fez, Morocco
World Journal of Advanced Research and Reviews, 2026, 30(02),1127-1131
Article DOI: 10.30574/wjarr.2026.30.2.1277
Received on 30 March 2026; revised on 13 May 2026; accepted on 15 May 2026
Primary breast sarcomas are exceptionally uncommon, and rhabdomyosarcoma represents an even rarer subset that is predominantly encountered in younger populations. The embryonal form arising in the breast is particularly unusual and is recognized for its highly aggressive behavior. We describe a patient who presented with a rapidly progressive breast mass associated with distant metastatic involvement.
Histopathological and immunohistochemical evaluation revealed features consistent with embryonal rhabdomyosarcoma, showing evidence of skeletal muscle differentiation. The clinical evolution was marked by swift deterioration, and the patient succumbed to the disease shortly after diagnosis, before any therapeutic strategy could be implemented. This case underscores the exceptional nature of breast embryonal rhabdomyosarcoma in adults and illustrates the diagnostic and therapeutic challenges posed by its fulminant progression, emphasizing the need for heightened clinical suspicion and prompt pathological assessment despite the generally unfavorable prognosis.
Adult rhabdomyosarcoma; Aggressive malignancy; Breast sarcoma, Embryonal rhabdomyosarcoma; Primary breast tumor; Poor prognosis
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Sara Nejjari, Mehdi Alem, Diango Keita, Lamiae Amaadour, Karima Oualla, Zineb Benbrahim Samia Arifi and Nawfel Mellas. Not your usual breast tumor: An unexpected embryonal rhabdomyosarcoma. World Journal of Advanced Research and Reviews, 2026, 30(02), 1127-1131. Article DOI: https://doi.org/10.30574/wjarr.2026.30.2.1277