Autoimmune Thyroid Dysfunction (Hashimoto’s Thyroiditis): Bridging TSH and Anti-TPO with Dosha-Based Pathogenesis

Hashimoto’s Thyroiditis is a scenario where there is a complex interplay between endocrine and immune system imbalances. Although modern medicine has highly benefited from hormone replacement therapy (Levothyroxine), this modality of treatment has often failed to address the underlying metabolic cause, namely involvement of metabolic toxins (Ama) and individual constitution (Prakriti). This article examines the relationship between modern biomarkers (TSH, Anti-TPO) and Ayurvedic pathogenesis (Samprapti), and presents a new clinical paradigm in which Anti-TPO titers are used as a measure of Ama (metabolic toxins) severity and Vata aggravation.