Postpartum depression and the scarcity of generalizable evidence: A mini-review of existing literature and the way forward

Fidelis E Uwumiro 1, *, Victory O Okpujie 2 and Kingsley O Anokwuru 1

1 Our Lady of Apostles Hospital, Akwanga, Nasarawa State, Nigeria.
2 Central Hospital Benin, Benin city, Edo State, Nigeria.
 
Review Article
World Journal of Advanced Research and Reviews, 2021, 11(02), 081–084
Article DOI: 10.30574/wjarr.2021.11.2.0364
 
Publication history: 
Received on 30 June 2021; revised on 04 August 2021; accepted on 06 August 2021
 
Abstract: 
The first known reference to Postpartum Depression (PPD), was Hippocrates’ 4th century hypothesis that drainage of lochia, if suppressed, could flow to the brain resulting in agitation, delirium, and episodes of mania. This hypothesis became dogma and lasted over a millennium. Over the years, knowledge of PPD has evolved but researchers still struggle to establish it as a distinct disease entity. It was initially recognized as Major Depressive Disorder (MDD) with postpartum onset in the 1994 revision of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV), the “bible” of diagnostic criteria for mental health professionals and researchers. It is currently recognized as MDD with peripartum onset (DSM-V) and researchers have admitted that persuasive evidence to indicate that postpartum depression is distinct from other existing depressive disorders, has not been found. Several diagnostic tools such as the Edinburg Postpartum Depression Scale (EDPS), the Beck Depression Inventory (BDI-II), Patient Health Questionnaire (PHQ-9), and the Postpartum Depression Screening Scale (PDSS) are available for use but none of these is universally accepted. With much of the published literature plagued with bias and structural inconsistencies, the credibility of the evidence has been greatly diminished. The difficulty with disease designation, the absence of a universally accepted tool for diagnosis and the scarcity of generalizable evidence on the subject has impaired the early recognition and effective management of PPD. It is therefore expedient, to critically appraise some of the available literature and proffer solutions to navigating this conundrum. 
 
Keywords: 
Postpartum depression; Perinatal depression; Infanticide; Depressive disorders; Depression in pregnancy
 
Full text article in PDF: 
Share this