False-positive diagnosis of uterine malignancy with raised 18F-fluorodeoxyglucose activity in adenomyosis: A case report

Wu Shun Felix Wong 1, * and Kwok To Thomas Li 2

1 Department of Obstetrics and Gynaecology, School of Women’s and Children’s Health, The University of New South Wales, Sydney, Australia.
2 Department of Obstetrics and Gynaecology, Queen Mary Hospital, The University of Hong Kong, China.
 
Case Study
World Journal of Advanced Research and Reviews, 2022, 13(02), 367–370
Article DOI: 10.30574/wjarr.2022.13.2.0178
 
Publication history: 
Received on 18 January 2022; revised on 19 February 2022; accepted on 21 February 2022
 
Abstract: 
Positron Emission Tomography - Computed Tomography (PET-CT) has been used to diagnose malignancy before surgery. However, there may be an increase in 18F-fluorodeoxyglucose (FDG) uptake in PET scans in benign conditions, leading to a false-positive diagnosis of malignancy and unnecessary surgery. This PET-CT investigation is expensive and is not without risk, including radiation and drug or contrast hypersensitivity. Although variable uterine uptakes of FDG activities in PET-CT had been reported in the literature, unawareness of its possibility in benign conditions could lead to a false alarm of malignancy. This paper reported a patient with a false-positive FDG finding presenting as a malignant uterine lesion for surgery, aiming to raise the clinical awareness of this finding.
 
Keywords: 
False-positive diagnosis; PET-CT; Adenomyosis; 18 F-fluorodeoxyglucose; Raised CA125
 
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