1 Medical Program, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
2 Department of Internal Medicine, Endocrinology and Metabolic Division, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
3 Department of Anatomical Pathology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
Research Article
World Journal of Advanced Research and Reviews, 2022, 16(03), 518-525
Article DOI: 10.30574/wjarr.2022.16.3.1363
Received on 07 November 2022; revised on 15 December 2022; accepted on 17 December 2022
The primary cause of hypothyroidism in the sufficient iodine area is Hashimoto's thyroiditis. Hashimoto's thyroiditis, also known as chronic autoimmune thyroiditis or chronic lymphocytic thyroiditis, is an autoimmune condition in which B cells and T cells slowly destroy the thyroid gland. To determine the diagnosis, we need the clinical, laboratory, cytological, and/or histopathology profiles. It aims to distinguish Hashimoto's thyroiditis from other diseases such as nontoxic goiter and Graves' disease. This retrospective descriptive study used data from the medical record of Dr. Soetomo General Hospital from 2015-2020. This study used total sampling and got 18 patients in total. The patients were mostly females (n=15), in the age group of 40-49 years old (n=8). The main complaint was an enlargement or nodule in the neck. The TSH (thyroid stimulating hormone) levels were majorly higher than the normal range (n=8) meanwhile the FT4 levels were mostly normal (n=6) and low (n=6). The positivity of TPOAb (antibody against thyroid peroxidase) is merely found in one patient. The majority of the result of the Doppler ultrasound examinations revealed Hashimoto’s thyroiditis (n=7). FNAB (fine needle aspiration biopsy) was performed on 11 patients. A histopathology examination was also conducted on 9 patients who underwent thyroidectomy. All of the cytology and histopathology examinations confirmed Hashimoto’s thyroiditis. Non-Hodgkin Lymphoma was found to coexist with 2 Hashimoto's thyroiditis cases. The findings were similar to the previous studies, except that among all the subjects, those who are 40-49 in age were primarily found in this study.
Hashimoto’s Thyroiditis; Autoimmune Thyroiditis; Clinical Profile; Laboratory Profile; Cytological Profile; Histopathological Profile
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Shisilia Mitra Novita, Rio Wironegoro and Dyah Fauziah. The clinical, laboratory and anatomical pathology profiles of Hashimoto’s Thyroiditis patients at Dr. Soetomo General Academic Hospital Surabaya 2015 – 2020. World Journal of Advanced Research and Reviews, 2022, 16(3), 518-525. Article DOI: https://doi.org/10.30574/wjarr.2022.16.3.1363