1 Department of Biological Sciences, Kisii University, School of Pure and Applied Sciences, P. O. Box 408-40200, Kisii, Kenya.
2 Clinical Trials Unit, Directorate of Product Safety, National Drug Authority, P.O Box 23069, Kampala, Uganda.
3 Poompuhar College, Melaiyur 609 107, Sirkali Taluk, Nagapattinam District, India.
Research Article
World Journal of Advanced Research and Reviews, 2024, 21(03), 1466–1475
Received on 13 December 2023; revised on 24 February 2024; accepted on 17 March 2024
Our previous findings showed that amines from Tridax procumbens (Family: Asteraceae) were responsible for the synthesis of silver nanoparticles. T. procumbens is a weed plant with rich source of medicinal compounds. In the current work, we studied the initial characterization of bioactive compounds by LC-MS, an essential tool for the characterization and identification of low molecular compounds. Further the isolated compounds were investigated for silver nanoparticle synthesis. The leaf extracts examined revealed many novel amine derivative compounds reported for the first time mainly belonging to the group of free amines: n-Pentylhydrazine hydrochloride, 2-Nitrobenzenesulfonyl chloride, 1,7-Dichlorooctamethyltetrasiloxane, 5-Chloro-1,2,4-trihydroxybenzene, 3-Chloro-2-hydroxy-5-(trifluoromethyl)pyridine and 2-(Diphenylphosphino) ethyltriethoxysilane and conjugated amines: 5-Methoxy-diisopropyltryptamine, 4-Chlorophenoxyacetic acid, Diphenhydramine, Erucamide, n(4-((2-(2,5-dimethoxybenzylidene)hydrazino)carbonyl)ph)-4-me-benzenesulfonamide and 1,3,5-Trithia-2,4,6-tristannacyclohexane, 2,2,4,4,6,6-hexamethyl. Characterization by UV-Vis spectra, XRD, EDX and TEM revealed well separated spherical shaped AgNPs size ranging 8-50 nm. These findings suggest that further work could be extended to isolate and elucidate the structures of the identified molecules using powerful instruments such as HPLC-MS, HPLC-NMR and high resolution-MS (HR-MS). Further biotechnological approaches towards synthesis of novel metals will be enhanced to promote green chemistry technology for the synthesis of nanoparticles.
Silver nanoparticles; LC-MS; Tridax procumbens; Amines
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Ondari Erick Nyakundi, Nyabengi Vane Bonareri, Tukamuhebwa Joanitor and M. Nalini. Characterization of Tridax procumbens amines with a potential to synthesize silver nanoparticles. World Journal of Advanced Research and Reviews, 2024, 21(3), 1466-1475. Article DOI: https://doi.org/10.30574/wjarr.2024.21.3.0321