Deciphering the Genetic Code: Mechanisms, Evolution, and Implications for Biotechnology
Department of Microbiology, Skyline University Nigeria.
Review Article
World Journal of Advanced Research and Reviews, 2024, 21(01), 858–868
Publication history:
Received on 24 September 2023; revised on 06 January 2024; accepted on 09 January 2024
Abstract:
The study of the genetic code explores the foundational language of life, aiming to fathom how DNA orchestrates the synthesis of proteins. This study explores various facets of the genetic code, from the widespread use of the triplet codon system to the vital role of transfer RNA (tRNA) in translation. This study unravels the intricacies of interactions between codons and anticodons, as well as the orchestration of ribosomes, casting illumination on the initiation, elongation, and termination stages of protein synthesis. Furthermore, it delves into the regulatory factors and mechanisms for quality control that wield influence over the translation processes. In the exploration of the genetic code's evolution, the study meticulously examines its universal principles, exceptions, and the compelling conjectures enveloping its origins. The coevolution of tRNA and codons, along with adaptations in the code observed in diverse organisms and organelles, yields valuable insights. Notably, the research underscores the vast biotechnological applications encompassing genetic engineering, codon optimization, and protein design. This study not only addresses uncharted territories in genetic code research but also propounds future research directions. It highlights current challenges and opportunities within this domain, including code expansion and gene editing advancement. Ultimately, the study of the genetic code remains a dynamic, ever-evolving field with profound implications for science, technology, and our comprehension of life's fundamental processes. This research unravels the captivating narrative of the genetic code, revealing novel areas and applications that continue to captivate and inspire.
Keywords:
Genetic code; Codon-anticodon interactions; Translation; Biotechnology; Evolution
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Copyright © 2024 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0