Faculty of Veterinary, Department of Biochemistry, Ataturk University, Erzurum, Turkey.
Research Article
World Journal of Advanced Research and Reviews, 2021, 12(02), 179–184
Received on 26 September 2021; revised on 07 November 2021; accepted on 09 November 2021
HCT116 cells are adherent epithelial cells derived from the human colorectal carcinoma cell line commonly used to study inflammatory responses in colonic epithelial cells. In this study, it was aimed to evaluate the effects of active anionic H2O8 oxygen solution, which is a very strong antiviral and antimicrobial agent, on HCT-116 human colorectal cancer cell line. Cell viability was determined by MTT analysis. Antiproliferative activity of the anionic H2O8 was investigated on HCT 116 (human colorectal carcinoma) cancer cells. Anionic H2O8 displayed the outstanding activities for MTT test, IC50= 9.44 for 24th hour was calculated as IC50= 11.73 for 48th hour on HCT 116 cell line. It is thought that it can serve as an agent with strong potential to be used in treatment.
Active anionic oxygen; Cancer; HCT 116; Cell; MTT.
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Apaydin Yildirim Betul. Anti-cancer, antiproliferative activity of active anionic H2O8 oxygen solution on HCT-116 cancer cell. World Journal of Advanced Research and Reviews, 2021, 12(2), 179-184. Article DOI: https://doi.org/10.30574/wjarr.2021.12.2.0560