Current aspects in the management of COVID 19

Shashidhar Binnamangala Gangappa 1, Abhishekh Basavarajegowda 2, * and Srikanth Umakanthan 3

1 Consultant, Critical Care, Vikram Hospital, Bengaluru, Karnataka, India.
2 Associate Professor, Department of Transfusion Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research(JIPMER), Puducherry, India
3 Faculty, Department of Paraclinical Sciences, The University of the West Indies, Mount Hope, Trinidad and Tobago
 
Review Article
World Journal of Advanced Research and Reviews, 2020, 08(01), 086-092
Article DOI: 10.30574/wjarr.2020.8.1.0363
 
Publication history: 
Received on 29 September 2020; revised on 07 October 2020; accepted on 11 October 2020
 
Abstract: 
Diagnosis and management of emerging infections like COVID 19 is a combination of clinical, epidemiological, and laboratory considerations. The mainstay of diagnosis is RT-PCR from oro-nasal swabs. Other blood investigations for hematology and biochemistry and imaging for chest infections can be supportive and may have prognostic value. Clinical management mainly involves supportive care as any acute care lung infections and sepsis, oxygen therapy, either invasive or non-invasive, as applicable. Corticosteroid therapy and anticoagulation are known to somewhat effective. Ivermectin, Tocilizumab, Favipiravir, and Remdesivir have shown to be of some benefit. Convalescent plasma therapy has been tried with not much evidence of benefit. Conclusive evidence for any particular modality of treatment is yet to be published. It is pertinent to understand that the successful management of critically ill patients with multi-system involvement requires a concerted holistic approach with multidisciplinary care. 
 
Keywords: 
Covid-19; Management; Diagnosis; Ventilation
 
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