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eISSN: 2581-9615 || CODEN: WJARAI || Impact Factor 8.2 ||  CrossRef DOI

Research and review articles are invited for publication in April 2026 (Volume 30, Issue 1) Submit manuscript

Comparison of trace element contents in normal thyroid and thyroid with Hashimoto's thyroiditis using neutron activation analysis

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  • Comparison of trace element contents in normal thyroid and thyroid with Hashimoto's thyroiditis using neutron activation analysis

Vladimir Zaichick *

Radionuclide Diagnostics Department Medical Radiological Research Centre Obninsk, Russia.
 
Research Article
World Journal of Advanced Research and Reviews, 2021, 12(01), 503-511
Article DOI: 10.30574/wjarr.2021.12.1.0558
DOI url: https://doi.org/10.30574/wjarr.2021.12.1.0558
 
Received on 25 September 2021; revised on 28 October 2021; accepted on 30 October 2021
 
Role of trace elements (TE) in etiology and pathogenesis of Hashimoto's thyroiditis (HT) is unclear. The aim of this exploratory study was to assess whether there were significant changes in thyroid tissue levels of ten TE (Ag, Co, Cr, Fe, Hg, Rb, Sb, Sc, Se, and Zn) are present in the autoimmune transformed thyroid. Ten TE of thyroid tissue were determined in 8 patients with HT and 105 healthy populations. The measurements were performed using non-destructive instrumental neutron activation analysis with high resolution spectrometry of long-lived radionuclides. Elevated mean values of Ag, Hg, and Rb content were found in thyroid with HT in comparison with normal level (in approximately 21, 30, and 1.6 times, respectively). Because the considerable changes in some TE contents in tissue of thyroid with HT were found, it is reasonable to assume that the levels of these TE in thyroid tissue can be used as HT markers. However, this topic needs additional studies.
 
Hashimoto's thyroiditis; Thyroid; Trace elements; Neutron activation analysis
 
https://wjarr.com/sites/default/files/fulltext_pdf/WJARR-2021-0558.pdf

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Vladimir Zaichick. Comparison of trace element contents in normal thyroid and thyroid with Hashimoto's thyroiditis using neutron activation analysis. World Journal of Advanced Research and Reviews, 2021, 12(1), 503-511. Article DOI: https://doi.org/10.30574/wjarr.2021.12.1.0558

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