A review on the treatment of heamotogenoues osteomylitis

Joan Nakibuuka Nyeenya 1, 3, Jeminah Nakatudde Nyeenya 2, Chunzhi Jiang 3, Lee Han 4, Lydia Mukanhaire 1 and Xiaohui Zhou 1, *

1 School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu, China.
2 Xuzhou Medical University, Xuzhou,Jiangsu 221004, China.
3 Department of Orthopedics, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, 210029, China.
4 Jiangsu Health Vocational College, Nanjing, Jiangsu,210029, China.
 
Review Article
World Journal of Advanced Research and Reviews, 2023, 20(02), 1312–1322
Article DOI: 10.30574/wjarr.2023.20.2.2397
 
Publication history: 
Received on 12 October 2023; revised on 20 November 2023; accepted on 23 November 2023
 
Abstract: 
In clinical parlance, a new infection in the bone is referred to as acute osteomyelitis. This illness is more common in youngsters and spreads through the bloodstream rather than through direct contact. When it occurs in adulthood, osteomyelitis is typically a subacute or chronic infection that develops as a consequence of an open injury to the bone and the soft tissue that surrounds it. In cases of bacterial osteomyelitis, the patient's age or a typical clinical scenario is frequently connected to the particular organism that was isolated from the disease. (i.e., trauma or recent surgery). Staphylococcus aureus has been linked to the condition in the vast majority of patients who have experienced acute hematogenous osteomyelitis. Patients who have chronic osteomyelitis frequently have bacteria such as Staphylococcus epidermidis, Staphylococcus aureus, Pseudomonas aeruginosa, Serratia marcescens, and Escherichia coli isolated from their bodies. In order to achieve the optimum results, antibiotic treatment should begin as soon as feasible, and antimicrobial medications should be managed parenterally for a minimum of four to six weeks. Standard components of treatment include evaluation, staging, assessment of microbiological aetiology and susceptibilities, antibiotic therapy, and, if required, debridement, dead-space management, and bone stabilization.
 
Keywords: 
Osteomyelitis; Surgical Debridement; Infection; Diabetes Mellitus
 
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