Novel Nanocarrier - A Research Article's Review on Nanosponges"
1 Department of Pharmaceutics, Sri Ramachandra Faculty of Pharmacy, Sri Ramachandra Institute of Higher Education and Research (DU), Chennai, India.
2 Sri Ramachandra Faculty of Pharmacy, Sri Ramachandra Institute of Higher Education and Research (DU), Chennai, India.
Review Article
World Journal of Advanced Research and Reviews, 2023, 20(02), 377–388
Publication history:
Received on 26 September 2023; revised on 06 November 2023; accepted on 08 November 2023
Abstract:
The process of modern medication delivery system development is smooth. Any delivery method that directs a molecule to a specific place is always valued. A specialised drug delivery system can easily target the medicine at the site of action without sacrificing its efficacy and quality, satisfying this criterion. Most novel medications can be administered effectively using a conventional dose form. Benefits from localised, focused distribution of therapeutic substances are thus additional factors influencing the current situation. With the introduction of nanosponge technology, systemic toxicity and extreme reactions can be reduced by helping the drug release gradually and in a controlled manner. With cavities that can be filled with a wide range of hydrophilic and hydrophobic drugs, nanosponges, which are tiny sponges about the size of a virus (250 nm-1µm), can be further incorporated into a pharmaceutical dosage form such as oral, parenteral, topical, or inhalation. The discovery of nanosponge has proven to be a significant stride in the fight against issues including patient unacceptability, medication toxicity, poor bioavailability, and physiochemical instability. There are six different methodologies for the preparation of the nanosponges which follows a particular mechanism for the release of the drug from it. Further, the nanosponges can be subjected to several characterization.
Keywords:
Characterization; Mechanism; Methodology; Nanosponges; Target Site
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