Acute Pancreatitis: A clinical perspective

Carlos Daniel Orozco Sierra 1, *, Reiner León Cifuentes 1, Daniela Rodríguez Sierra 2, Mayra Manrique 1, Víctor Jaimes 1 and David Fernando Farah Borrero 1

1 Department of Internal Medicine, Faculty of Health Sciences, Libre University, Barranquilla, Colombia.
2 Medicine Program, Faculty of Health Sciences, Del Norte University, Barranquilla, Colombia. 
 
Review Article
World Journal of Advanced Research and Reviews, 2023, 19(03), 813–823
Article DOI: 10.30574/wjarr.2023.19.3.1901
 
Publication history: 
Received on 08 August 2023; revised on 17 September 2023; accepted on 19 September 2023
 
Abstract: 
Acute pancreatitis is one of the main gastrointestinal disorders that is characterized by an acute inflammatory process of the pancreatic tissue with variability in severity, usually with a mild and self-limiting presentation, and presenting a low mortality. Biliary etiology is the leading cause of acute pancreatitis worldwide, with greater involvement in the female gender. Within the diagnostic approach, acute abdominal pain and intense onset in the epigastrium radiating to the back is usually the most representative symptom that leads to suspicion of this entity, accompanied by elevation of pancreatic enzymes and the presence of typical image findings of inflammation of the pancreas.  The objection to identifying which patients are at risk of developing local or systemic complications has led to the creation of different scales predicting the severity of pancreatitis with performances that are still debatable. Therapeutic management has two fundamental pillars, fluid resuscitation to maintain or restore tissue perfusion and adequate nutritional support to counteract the catabolic state and reduce the rate of infectious complications. In the context in which the cause is a biliary origin, its resolution is important to avoid progression to chronic pancreatitis.
 
Keywords: 
Pancreatitis; Acute; Amylase; Abdominal Pain; BISAP.
 
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