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eISSN: 2581-9615 || CODEN: WJARAI || Impact Factor 8.2 ||  CrossRef DOI

Research and review articles are invited for publication in March 2026 (Volume 29, Issue 3) Submit manuscript

Synergism between platelet-rich fibrin with superpulsed laser and pulsed magnetic field in the treatment of disc herniations: A therapeutic protocol v

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  • Synergism between platelet-rich fibrin with superpulsed laser and pulsed magnetic field in the treatment of disc herniations: A therapeutic protocol v

Palmerindo Antônio Tavares de Mendonça Néto 1, *, Douglas Scott Johnson 2, Dana York 3, Dirceu Moraes Junior 4, Carlos Stéfano Hoffmann Brito 5, Daniel Ramos Gonçalves Lopes 6 and Mayara Magda Dantas Tavares de Mendonça 1

1 Regenera Dor Institute, Juazeiro do Norte, Ce, Brazil.

2 Senior Visiting Fellow, Laboratory of Phototherapy and Innovative Technologies; São Paulo, Sp, Brazil. 

3 European Medical Laser Association; New York, Ny, EUA. 

4 Clinical Lumius; Joinville, Sc, Brazil. 

5 Carlos Stéfano Institute; Belo Horizonte, Mg, Brazil. 

6 Gaio and Lopes Specialty Medicine; Rio de Janeiro, Rj, Brazil.

Research Article

World Journal of Advanced Research and Reviews, 2025, 25(02), 593-608

Article DOI: 10.30574/wjarr.2025.25.2.0415

DOI url: https://doi.org/10.30574/wjarr.2025.25.2.0415

Received on 28 December 2024; revised on 02 February 2025; accepted on 05 February 2025

Herniated discs affect about 1% to 5% of the general population and are more common in adults between the ages of 30 and 50 years, the peak of productive age. Among the risk factors are obesity, sedentary lifestyle and activities that involve weightlifting. This condition often results in chronic pain, depression, work disability, and reduced daily functional capacity. Clinically, patients present with localized pain with or without irradiation, muscle weakness, tingling, and, in more severe cases, loss of sensation. The definitive diagnosis is obtained through imaging tests, such as CT scans or MRIs, which allow confirmation of the extent and location of the hernia. Therapeutic options range from conservative approaches, including physical therapy and analgesic and anti-inflammatory medications, to surgical interventions for cases where there is significant neurological impairment. Recently, innovative therapies such as superpulsed laser, pulsed magnetic field, and Orthobiological, such as injectable platelet-rich fibrin, have shown promising results. The combination of orthobiologicals with superpulsed laser and pulsed magnetic field offers an integrated approach to modulate the inflammatory response and promote tissue regeneration. This therapeutic synergy can provide effective symptomatic relief, injured tissue repair, and accelerated recovery. The regenerative approach to herniated discs, which combines orthobiological, superpulsed laser, and pulsed magnetic field, has the potential to revolutionize treatment by offering a minimally invasive, safe, and effective option for patients. Additional studies are needed to evaluate the statistical effectiveness and side effects of this innovative approach. 

Disc hernia; Non-surgical treatment; Minimally invasive treatment; Regenerative medicine; Orthobiological; Superpulsed laser treatment; Pulsed magnetic field

https://wjarr.com/sites/default/files/fulltext_pdf/WJARR-2025-0415.pdf

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Palmerindo Antônio Tavares de Mendonça Néto, Douglas Scott Johnson, Dana York, Dirceu Moraes Junior, Carlos Stéfano Hoffmann Brito, Daniel Ramos Gonçalves Lopes and Mayara Magda Dantas Tavares de Mendonça. Synergism between platelet-rich fibrin with superpulsed laser and pulsed magnetic field in the treatment of disc herniations: A therapeutic protocol v. World Journal of Advanced Research and Reviews, 2025, 25(2), 593-608. Article DOI: https://doi.org/10.30574/wjarr.2025.25.2.0415

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