Future perspectives on neonatal brain injury

Maria Tzeli 1, Maria Tigka 1, 2, *, Nikoletta Pantelaki 1, Eleftheria Lazarou 3 and Dimitra Metallinou 1

1 Department of Midwifery, School of Health and Care Sciences, University of West Attica, 28 Ag. Spyridonos Str., GR-12243, Athens, Greece.
2 Department of Obstetric Emergency, General and Maternity Hospital 'Helena Venizelou', 2 Elenas Venizelou Str., GR-11521, Athens, Greece.
3 Department of Nursing, School of Health Sciences, Cyprus University of Technology, 30 Arch. Kyprianos Str., CY-3036, Limassol, Cyprus.
 
Review Article
World Journal of Advanced Research and Reviews, 2023, 19(03), 651–657
Article DOI: 10.30574/wjarr.2023.19.3.1846
 
Publication history: 
Received on 03 August 2023; revised on 09 September 2023; accepted on 12 September 2023
 
Abstract: 
Neonatal brain injury (NBI) is a complex and challenging area of research and critical care. Advances in understanding and treating NBI are crucial for improving the long-term adverse neurological outcomes of the affected neonates. Future perspectives in NBI are focused on systematic antenatal education, personalized medicine and profiling, stem cell and neuroprotective therapies, biomarkers in biological fluids with an emphasis on multimodal biomarker panels, collaborative research projects and considerations regarding ethical issues. Although substantial efforts have been made recently to restrain NBI, its incidence is still high on a global scale. Therefore, future management of NBI will involve a multidisciplinary approach that integrates genetics, individualized therapy, and medical advancements, with particular attention to early detection and intervention. The ultimate goal is to reduce the prevalence of NBI and improve the affected neonates' long-term prognosis. It is critical to remember that this field of study is still being investigated, and it could be years before many of these advancements are widely applied in standard clinical practice.
 
Keywords: 
Future perspectives; Neonatal; Brain; Injury; Advancements
 
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