Prostate Cancer Volumetric Arc Therapy (VMAT) Analysis
Genesiscare, Radiation Oncology, Modesto, California, USA.
Research Article
World Journal of Advanced Research and Reviews, 2023, 19(01), 1033–1044
Publication history:
Received on 04 June 2023; revised on 11 July 2023; accepted on 13 July 2023
Abstract:
Aim: The purpose of this study was to derive radiobiological parameters from the dose volume histogram of patients that undergone prostate cancer radiotherapy via the VMAT technique.
Material and Methods: A total of twenty-two cases of prostate cancer of 70.2 and 81 Gy were selected for this study. Radiobiological parameters were evaluated by the Poisson equation for the tumor and LKB model for organs at risk.
Results: For prostate tumor, the average TCP was 96.28, 86.45, 68.57 for α/β of 1.2, 3.0, and 10, respectively. The average EUD was 37.98 Gy, 59.23 Gy, 21.19 Gy, 20.65 Gy, 16.32 Gy, and 21.87 Gy for bladder, rectum, right femoral head, left femoral head, small bowel, and large bowel respectively. The average NTCP was 7.6 % for the rectum and negligible for other organs at risk.
Conclusion: NTCP for critical organs and TCP for prostate cancer can be determined via dose volume histogram.
Keywords:
Equivalent uniform dose; Normal tissue complication probability; Prostate cancer; VMAT; Tumor control probability
Full text article in PDF:
Copyright information:
Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0