Uremic leontiasis ossea: A pictorial review of a rare complication of renal osteodystrophy
1 Department of radiology, CHU Hassan II, University of Sidi Mohammed Ben Abdallah, Fez, Morocco.
2 Department of head and neck surgery, CHU Hassan II, University of Sidi Mohammed Ben Abdallah, Fez, Morocco.
Review Article
World Journal of Advanced Research and Reviews, 2023, 19(01), 800–814
Article DOI: 10.30574/wjarr.2023.19.1.1414
Publication history:
Received on 05 June 2023; revised on 12 July 2023; accepted on 14 July 2023
Abstract:
Uremic leontiasis ossea is a very rare manifestation of renal osteodystrophy with associated secondary or tertiary hyperparathyroidism, resulting in a diffuse and symmetrical enlargement of the craniofacial bones.
Although its pathophysiology remains uncertain, it seems that hyperphosphatemia and hypocalcemia secondary to chronic renal failure are the most likely precipitating factors.
Information regarding this disease consists mainly of case reports in the literature and some small series.
We describe four patients with ESRD on hemodialysis who had chronic progressive facial deformities and underwent imaging of the head and neck for further evaluation.
The aim of this work is to describe the characteristic imaging appearance of ULO and provide a broad review regarding its physiopathology, clinical presentation, biological assessment and treatment.
Knowledge of this disease is essential for every clinician involved in treating ESRD patients since treatment options aim to control hyperparathyroidism, resulting in stabilization of the facial deformities in most cases.
Keywords:
uremic leontiasis ossea; Hyperparathyroidism; Hyperphosphatemia; CT scan; Renal osteodystrophy
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Copyright © 2023 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0