1 Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
2 Department of Clinical Microbiology, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
3 Department of Anesthesiology and Reanimation, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
4 Department of Pulmonology and Respiratory Medicine, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
Research Article
World Journal of Advanced Research and Reviews, 2024, 24(03), 1723-1730
Article DOI: 10.30574/wjarr.2024.24.3.3826
Received on 05 November 2024; revised on 12 December 2024; accepted on 14 December 2024
Introduction: Stenotrophomonas maltophilia is a challenging respiratory tract pathogen with increasing number of cases. S. maltophilia also shows a high resistance towards various antibiotics. The aim for this study is to know the antibiotic resistance pattern and profile of patient infected with S. maltophilia in order to find out effective antibiotic therapy in treating future cases.
Methods: This cross-sectional study uses descriptive analytic method using medical record data of 36 patients infected with S. maltophilia in Dr. Soetomo General Academic Hospital during 2020-2022 period. The measured variables included antibiotic resistance pattern, age, sex, clinical diagnosis, comorbidity, signs and symptoms, medical device usage, total leukocyte count, and mortality rate.
Result: S. maltophilia shows highest sensitivity index towards Trimetophrim-sulfomethoxazole (56%). Cases of S. maltophilia is most often found in 0-17 years age group (53%) and male (63%). It may cause infection whether alone or alongside other bacteria. The most common clinical diagnosis that occurs in S. maltophilia infections is pneumonia (81%). Dyspnea is the most occurred symptoms. Hypertension is a common comorbidity. IV infusion is the most used medical device. Might cause infection alongside other bacteria. Leukocytosis is often present. Mortality rate among subjects is 50%.
Conclusion: Trimetophrim-sulfomethoxazole is the best treatment for S. maltophilia infections. Cases most often occurs in age 0-17 years, male, diagnosed with pneumonia, and has hypertension as comorbidity. In the future, antibiotics must be used wisely to prevent bacterial resistance and regular changing of medical device is encouraged to prevent nosocomial infections.
Stenotrophomonas maltophilia; Antibiotic resistance; Bacterial infection; Patient profile; Pneumonia
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Fauzia Rachma Diena, Eko Budi Koendhori, Anna Surgean Veterini and Tutik Kusmiati. Profile and resistance pattern of Stenotrophomonas maltophilia in Dr. Soetomo General Academic Hospital During 2020-2022 Period. World Journal of Advanced Research and Reviews, 2024, 24(3), 1723-1730. Article DOI: https://doi.org/10.30574/wjarr.2024.24.3.3826