Department of Surgery, Medical University of Agadir, Morocco.
Research Article
World Journal of Advanced Research and Reviews, 2024, 24(03), 337–342
Received on 27 October 2024; revised on 02 December 2024; accepted on 05 December 2024
Introduction: Tranexamic acid (TXA) is an antifibrinolytic agent used to control bleeding in surgery. This study investigates the efficacy and safety of intrathoracic TXA application in thoracic surgeries.
Objectives: To assess the reduction in blood transfusions and the need for reoperations, as well as the safety of intrathoracic TXA use.
Methods: A total of 13 patients (84% male, mean age 32 years) undergoing pleural decortication were treated with intrathoracic TXA (1.5 g in 250 cc saline). The solution remained in place for 15-20 minutes before being rinsed.
Results: 92% of patients did not require transfusions, no reoperations were necessary, and no mortalities were reported. Minor side effects were noted.
Conclusion: Intrathoracic TXA effectively reduces postoperative transfusion needs and is safe, with no major complications. Further studies are needed to confirm these findings
Pleura; Bleeding; Tranexamic acid; Thoracic surgery; Pleural instillation
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Mouad GOURTI, Mohamed Hachmi, Imane lefqih, Fatimzahra Ammor, Mouhsine Makloul and Elmehdi Maidi. Intrathoracic use of tranexamic acid: Reduction of transfusions and safety in thoracic surgery. World Journal of Advanced Research and Reviews, 2024, 24(3), 337-342. Article DOI: https://doi.org/10.30574/wjarr.2024.24.3.3704