Department of Paediatric Radiology, Hôpital Mère-enfant, Abderrahim Harouchi, Centre Hospitalier Universitaire Ibn Rochd, Casablanca, Morocco.
Research Article
World Journal of Advanced Research and Reviews, 2024, 24(03), 162–167
Received on 19 October 2024; revised on 26 November 2024; accepted on 29 November 2024
Congenital brain defects are abnormalities in brain development that occur during foetal life. These anomalies can have a variety of causes, including genetic factors, intrauterine infections, maternal exposure to toxins and disturbances in the intrauterine environment. Cerebral malformations can lead to drug-resistant epilepsy, one of a variety of neurological problems. The imaging of drug-resistant epilepsy is a critically important topic, as seizures that are refractory to drug treatment pose a significant challenge for clinicians. In children with congenital brain malformations, drug resistance is particularly common. Advances in brain imaging have led to significant improvements in diagnosis, localisation of epileptogenic foci and surgical planning. The main imaging techniques used, each of which has a role to play in the management of drug-resistant epilepsy, are magnetic resonance imaging (MRI), computed tomography (CT) and transfontaneous ultrasound (FUS). Five cases were collated to illustrate the different forms of cerebral malformations in children presenting with drug-resistant epileptic seizures at the Abderrahim Harouchi Mother and Child Hospital in Casablanca.
Epilepsy; Cerebral; Malformations; Drug-Resistant
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Donald Wilhem Aloumba-Gilius, Sami El Himri, Hiba Oudrhiri, Dalale Laoudiyi, Kamilia Chbani and Siham Salam. Imaging congenital brain malformations: A cause of drug-resistant epilepsy in children. World Journal of Advanced Research and Reviews, 2024, 24(3), 162-167. Article DOI: https://doi.org/10.30574/wjarr.2024.24.3.3644