1 Department of Obstetrics and Gynaecology, Korle-Bu Teaching Hospital, Korle-Bu, Accra, Ghana.
2 Department of Obstetrics and Gynaecology, University of Ghana Medical School, Korle-Bu, Accra, Ghana.
3 Department of Community Health, University of Ghana Medical School, Korle-Bu, Accra, Ghana.
4 Department of Electron Microscopy and Histopathology, Noguchi Memorial Institute of Medical Research.
Research Article
World Journal of Advanced Research and Reviews, 2024, 24(01), 2395-2406
Received on 16 September 2024; revised on 24 October 2024; accepted on 26 October 2024.
Introduction: Genitourinary syndrome of menopause (GSM) is a chronic, progressive, vulvovaginal, sexual, and lower urinary tract condition characterized by a broad spectrum of signs and symptoms. It is a consequence of the hypoestrogenic state associated with reproductive aging and impacts the quality of life of affected women. Even though the condition mainly affects postmenopausal women, it is seen in many premenopausal women as well This study sought to determine the prevalence, associated factors and quality of life impact associated with GSM among midlife women reporting for cervical routine screening in a tertiary hospital.
Method: A cross-sectional study of 400 women aged 40 to 60 years who had a routine cervical smear at the Korle Bu Teaching Hospital (KBTH) from February 2022 to September 2022. GSM was defined by using three parameters: one symptom of GSM, one physical sign of vaginal atrophy and vaginal pH > 5. Quality of life was determined using the Day-to Day Impact on Vaginal Aging (DIVA) Questionnaire. Multiple logistic regression was used to assess significant association and 95% confidence intervals calculated around the estimates generated.
Results: The prevalence of GSM was 46.8%. The most common symptom and sign was vaginal dryness (57%) and vaginal pallor (85%) respectively. Age, frequency of sexual activity and anogenital index were significantly associated with GSM. Participants with GSM had higher mean DIVA scores as well as higher scores for the sexual dysfunction and self-perception domains.
Conclusion: The study found a high prevalence of GSM significantly associated with increasing age, frequency of sexual activity and high anogenital index. As GSM negatively impacted the QoL of the women. It is important to screen and intervene early to improve QoL
Genitourinary syndrome; Menopause; Midlife; Anogenital index
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Paul. M. Adomako, Kwaku Asah-Opoku, Ali Samba, Kareem Mumuni, Emilia A Udofia and Morrison Asiamah. Genitourinary Syndrome of Menopause (GSM) and its impact on Quality of Life (QoL) among Midlife Women in Accra, Ghana. World Journal of Advanced Research and Reviews, 2024, 24(1), 2395-2406. Article DOI: https://doi.org/10.30574/wjarr.2024.24.1.3276