1 School of Pharmaceutical Sciences, RIMT University, Punjab, India.
2 Department of pharmaceutics, Mangalayatan University Alighar, Extended NCR 33 milestone Mathura Alighar highway mangalayatan University Beswan, India.
3 Department of pharmacology, Lords University Alwar - Bhiwadi Rd, Chikani, Rajasthan 301028, India.
4 Department of Pharmaceutics, Priyadarshani J. L. College of Pharmacy, Nagpur, Electronic zone Building, MIDC, Hingna road Nagpur-440016, India.
5 Pharmacognosy Lab, Tatyasaheb Kore college of pharmacy diploma Warananagar, A/P Warananagar near sugar factory, in the premises of shree Warana Vibhag shikshan mandal, 416113, India.
6 Pharmacology Laboratory, Tatyasaheb Kore college of pharmacy diploma Warananagar, A/P Warananagar near sugar factory, in the premises of shree Warana Vibhag shikshan mandal, 416113, India.
7 Department of Pharmacy, Gulabrao Patil College of Pharmacy, Miraj, Maharashtra, India.
Review Article
World Journal of Advanced Research and Reviews, 2024, 23(03), 141-160
Received on 19 July 2024; revised on 26 August 2024; accepted on 29 August 2024
The wide variety of bioactive substances found in medicinal plants has made them quite popular as of late. Several aspects of therapeutic plants are examined in this article. The basic concepts of phytochemicals are introduced, including where they come from, the roles they play in the body, and the latest methods for extracting them for use in nutraceuticals and functional foods. According to research shows that compared to conventional drugs, Apigenin and Alpha-Bisabolol exhibit far higher glide energy and docking scores. Cyperus scariosus and Parthenium hysterophorus are two examples of underappreciated plants whose nutritional and therapeutic potential, bioactive characteristics, and enzyme inhibitory powers are discussed. Molecular docking experiments are being conducted to see whether phytoconstituents can prevent diseases such as monkeypox, cardiovascular disease, epilepsy, and conjunctivitis; researchers are also investigating traditional therapies for COVID-19 and conjunctivitis. Adverse outcome pathways (AOP) and high-throughput techniques are two examples of modern methodological tools that have enhanced toxicological studies. The varied chemical compositions of primary and secondary metabolites have been the subject of qualitative and biochemical investigations that detail screening procedures. The paper concludes by discussing the bioactive features and their therapeutic uses, which include antimicrobial, cytotoxic, anti-inflammatory, and antiviral actions.
Bioactive; Disease and disorders; Extraction; Molecular docking; Phytochemicals
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Prabhjot Kaur, Rohitashwa sonkar, Nitin, Ragini Shubham Chaudhari, Vrunda Amol Jadhav, Nupur Omkar Kulkarni and Satheesh Vilas Patil. A review of medicinal plants: Phytochemicals, molecular docking, and bioactive properties. World Journal of Advanced Research and Reviews, 2024, 23(3), 141-160. Article DOI: https://doi.org/10.30574/wjarr.2024.23.3.2618