1 Department of Ophthalmology, Muhimbili University of Health & Allied Sciences. Box 65001, Dar es Salaam Tanzania.
2 School of Medicine, University of St Andrews, UK
Research Article
World Journal of Advanced Research and Reviews, 2021, 09(02), 127-133
Article DOI: 10.30574/wjarr.2021.9.2.0056
Received on 14 January 2021; revised on 15 February 2021; accepted on 17 February 2021
Background: Central Corneal Thickness (CCT) is an indicator of corneal health status as well as being an essential tool in assessment and management of corneal diseases. It is an important factor in the diagnosis and management of glaucoma as it affects the measurement of intraocular pressure. However, the pattern of central corneal thickness in our population is not known. Our study aimed to describe the CCT measurements and their variation with age and sex among patients attending the eye clinic at Muhimbili National Hospital (MNH), in Dar es Salaam, Tanzania.
Methodology: A hospital-based descriptive, cross-sectional study used convenient sampling to recruit adult patients aged 18 years and above, presenting to the MNH between August 2016 and January 2017.Visual acuity assessment, Goldman applanation tonometry and CCT assessment using an ultrasound pachymeter were performed. Patients with previous intraocular surgery were excluded.
Results: A total of 398 patients (208 males and 190 females) were recruited. The mean CCT was 526.64±38.30 µm; being 523.99±38.20 µm for males and 529.7±38.3 µm for females. 226 (56.85%) had CCT of less than 520 µm.There was no statistically significant difference in CCT between gender. The proportion of patients with thinner CCT increased with increasing age from 25.8% in those < 30 years to 75% in those aged 71years and above. The mean CCT decreased with increasing age with P-value<0.001.
Conclusion: The average CCT in patients attending Muhimbili National Hospital is 526.64 µm (SD 38.30) which is generally thin, inversely proportion to age and similar that of other Africans and African-Americans. This finding has implications for the management of glaucoma in this population.
Central Corneal Thickness; age; Africans
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Annamary Stanislaus, Ntsilane Susan Mosenene, Celina Mhina, John Stanslaus Kisimbi, Frederick Robert Burgess, Milka Madaha Mafwiri, Dilawar Padhan and Anna John Sanyiwa. The pattern of central corneal thickness in patients attending a Tertiary Hospital in Dar-Es-Salaam. World Journal of Advanced Research and Reviews, 2021, 9(2), 127-133. Article DOI: https://doi.org/10.30574/wjarr.2021.9.2.0056