1 Institute of Teaching, Research, and Innovation, Liga Contra o Câncer – Natal – Brazil.
Postgraduate Program in Biotechnology at Potiguar University, Potiguar University (UnP) – Natal/RN - Brazil.
2 Postgraduate Program in Biotechnology at Potiguar University/ UnP, Department of Surgery, Federal University of Rio Grande do Norte.
3 Department of Surgery, Potiguar University, Natal-RN, Brazil.
Review Article
World Journal of Advanced Research and Reviews, 2024, 23(01), 3030-3037
Received on 17 June 2024; revised on 27 July 2024; accepted on 30 July 2024
Long-term COVID-19 (Long COVID) and pulmonary thromboembolism (PTE) significantly challenge healthcare, especially in young adults who are typically at lower risk for such severe outcomes. This review explores the complex relationship between long-term COVID and PTE, focusing on the pathophysiological mechanisms, diagnostic challenges, and therapeutic approaches. Persistent inflammation and immune dysregulation associated with long-term COVID-19 contribute to this demographic's increased thrombotic risk. The symptom overlaps between long-term COVID and PTE complicate the accuracy and timeliness of diagnoses, highlighting the necessity for improved diagnostic strategies. Findings emphasize the need for anticoagulation protocols tailored to the specific clinical presentations of Long COVID patients and suggest that extended treatment durations may be beneficial. The potential of genetic and biomarker research to identify individuals at heightened risk of thrombotic complications is discussed. The review calls for a multidisciplinary approach that integrates medical and psychosocial interventions to manage the long-term effects of COVID-19 effectively. As the pandemic evolves, advancing our understanding and adapting healthcare strategies to these insights are crucial for developing effective clinical practices. This is essential for addressing the immediate health impacts and reducing the broader socioeconomic burdens associated with long-term COVID and PTE in young adults.
Long COVID; Pulmonary thromboembolism; Young adults; SARS-CoV-2; Anticoagulants; Thrombosis; Diagnosis; Physiopathology
Preview Article PDF
Amália Cinthia Meneses do Rêgo and Irami Araújo-Filho. Long COVID and lung thromboembolism in young adults. World Journal of Advanced Research and Reviews, 2024, 23(1), 3030-3037. Article DOI: https://doi.org/10.30574/wjarr.2024.23.1.2251