Tilak Maharashtra Vidyapeeth’s Lokmanya Tilak Institute of Pharmacy, Kharghar, Navi Mumbai Maharashtra, India.
Research Article
World Journal of Advanced Research and Reviews, 2024, 23(01), 649-661
Received on 28 May 2024; revised on 05 July 2024; accepted on 08 July 2024
The demand for natural and effective antimicrobial agents in oral care products has led to the exploration of botanical extracts such as Moringa and Neem. In this study, we aimed to prepare extracts from Moringa and Neem leaves and incorporate them into toothpaste formulations to evaluate their antimicrobial properties against oral pathogens.
The antimicrobial activity of the extracts was assessed using well-established agar diffusion assays against a panel of Gram-positive and Gram-negative oral bacteria. Additionally, the pH and consistency of the toothpaste formulations were optimized for usability and stability. Our results demonstrated significant antimicrobial activity of the Moringa and Neem extracts against a range of oral bacteria, including common pathogens associated with dental caries and periodontal diseases.
The formulated toothpaste containing these extracts exhibited promising inhibitory effects, suggesting their potential as natural alternatives or adjuncts to synthetic antimicrobial agents in oral hygiene products. This research work contributes to the ongoing exploration of plant-derived compounds for oral health applications.
Antimicrobial activity; Oral bacteria; Periodontal diseases; Dental carries
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Christina Viju John, Swati Suresh Pawane, Sayali Sandeep Marchande, Neha Sanjay Shinde, Abhishek Charudatta Patil, Rutuja Dattatray Machale and Shrutika Dipesh Patil. Formulation and evaluation of moringa and neem herbal toothpaste for comprehensive oral care. World Journal of Advanced Research and Reviews, 2024, 23(1), 649-661. Article DOI: https://doi.org/10.30574/wjarr.2024.23.1.2034