A critical review on formulation and evaluation of colon targeted drug delivery systems

Shivanshi Saini 1, *, Rajeev Tomar 1, Neha Saini 2, Devender Nath 2, Ramesh Kumar 2, Mohd. Haneef 3, Divyansh Kateja 3, Govind Upadhayay 3 and Yasir Ansari 3

1 Roorkee College of Pharmacy, Roorkee, Uttarakhand, India.
2 Glocal University, Saharanpur, Uttar Pradesh, India.
3 NIMS Institute of Pharmacy, NIMS University Rajasthan Jaipur, Rajasthan, India.
 
Review Article
World Journal of Advanced Research and Reviews, 2023, 17(02), 544–550
Article DOI: 10.30574/wjarr.2023.17.2.0305
 
Publication history: 
Received on 09 January 2023; revised on 16 February 2023; accepted on 20 February 2023
 
Abstract: 
A multidisciplinary scientific field that is fast growing is nanotechnology, often known as molecularly generated systems and technologies. Nanotechnology is a rapidly expanding field of applied science and engineering. It relies upon the concept of nano-scale manipulation of matter, meaning the ability to handle materials on a microscopic scale. Nanoparticles can be used to deliver a variety of substances, including conventional drugs, recombinant proteins, vaccines, and more recently nucleotides. Nanoparticles and other colloidal drug delivery techniques change the kinetics, body distribution, and drug release of a related drug. The treatment of negative effects and the distribution of therapy that targets certain tissues or cells are additional effects. As a result, nanoparticles in the pharmaceutical and biotechnology industries boost the therapeutic index and provide solutions to impending delivery problems for new classes of so-called biotech medicines such recombinant proteins and oligonucleotides.
 
Keywords: 
Nanoparticles; Colon; IBD; CDDS (Colon targeted drug delivery systems); Time-controlled release system (TCRS)
 
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