A comprehensive review on comparative study of Ayurveda and allopath in management of psoriasis
1 Roorkee College of Pharmacy, Roorkee Uttarakhand, India.
2 NIMS Institute of Pharmacy, NIMS University Rajasthan Jaipur, Rajasthan, India.
Research Article
World Journal of Advanced Research and Reviews, 2023, 17(01), 615-624
Article DOI: 10.30574/wjarr.2023.17.1.0108
Publication history:
Received on 12 December 2022; revised on 20 January 2023; accepted on 22 January 2023
Abstract:
A common skin disorder called psoriasis causes thickened patches of the skin. Typically, it is discovered to be covered with silvery scales. Although psoriasis is regarded as a skin condition, it is actually the outcome of an immune system dysfunction. Types of psoriasis-Plaque psoriasis (psoriasis vulgaris), Pustular psoriasis, Nail psoriasis, Guttate psoriasis, Flexural psoriasis, Erythrodermic psoriasis. Activated T cells go into the skin from the circulation and lymph nodes and release cytokines (INF, IL-2) that cause pathologic alterations. Other cytokines like TNF- and IL-8 are produced locally by neutrophils and keratinocytes. Keratinocyte proliferation is a result of T-cell generation and activation. Histocompatibility studies show relationships between histocompatibility antigens and HLA-C6, TNF, and IL-3.1)
· T-helper ½,
· Th17 & Th17 Cytokines,
· Dendritic cells, IL-23 and TNF-α.
They have many causes that help in develop the psoriasis are
· Genetics,
· Lifestyle,
· HIV,
· Microbes,
· Medications.
They have many treatment therapies are-
Topical therapy-
· Corticosteroids,
· Calcipotriene,
Tazarotene.
Keywords:
Psoriasis; Keratinocyte; Cytokines; Pustular psoriasis; Allopathy; Guttate psoriasis
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