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eISSN: 2581-9615 || CODEN: WJARAI || Impact Factor 8.2 ||  CrossRef DOI

Research and review articles are invited for publication in March 2026 (Volume 29, Issue 3) Submit manuscript

Review on therapeutic approach of anti-acne treatment by Azadirachta indica and Ocimum gratissimum

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  • Review on therapeutic approach of anti-acne treatment by Azadirachta indica and Ocimum gratissimum

Sonal Balasaheb Bangar *, Shreya Sandeep Bankar, Aditi Sunil Vibhute, Amit Rampal Yadav, Hrushikesh Ravindranath Pednekar, Lloyd Salu Dsilva and Shrutika Patil

TMV’s Lokmanya Tilak Institute of Pharmacy, Navi-Mumbai, Maharashtra, India.
 
Review Article
World Journal of Advanced Research and Reviews, 2024, 22(02), 165-174
Article DOI: 10.30574/wjarr.2024.22.2.1268
DOI url: https://doi.org/10.30574/wjarr.2024.22.2.1268
 
Received on 15 March 2024; revised on 25 April 2024; accepted on 27 April 2024
 
Millions of people worldwide suffer with acne vulgaris, a common skin ailment marked by the development of comedones, papules, pustules, and in more severe cases, nodules and cysts. There has been a boom in research into alternative remedies, especially herbal pharmaceuticals, due to growing resistance to traditional therapy and side effects associated with long-term use. Two well-known herbs with strong anti-acne effects are Ocimum gratissimum (scent leaf/ African basil) and Azadirachta indica (neem). The purpose of this review is to assess Azadirachta indica and Ocimum gratissimum's medicinal potential for acne vulgaris. We examine the phytochemistry of these herbs, emphasizing their potent components, which include thymol, eugenol, azadirachtin, nimbidin, and nimbin. These compounds have antibacterial, anti-inflammatory, and antioxidant qualities that make them useful in the treatment of acne. Finally, clinical studies examining the safety and effectiveness of topical formulations derived from Azadirachta indica and Ocimum gratissimum are reviewed, emphasizing their potential as monotherapies or adjuncts to conventional treatments. In summary, Azadirachta indica and Ocimum gratissimum represent promising candidates for the development of novel, effective, and safe herbal therapies for acne vulgaris, offering a natural alternative for people seeking sustainable and holistic approaches to skincare.
 
Azadirachta indica (Neem); Ocimum gratissimum (African Basil); Acne Therapy; Anti-Inflammatory; Antiseptic; Antioxidants
 
https://wjarr.com/sites/default/files/fulltext_pdf/WJARR-2024-1268.pdf

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Sonal Balasaheb Bangar, Shreya Sandeep Bankar, Aditi Sunil Vibhute, Amit Rampal Yadav, Hrushikesh Ravindranath Pednekar, Lloyd Salu Dsilva and Shrutika Patil. Review on therapeutic approach of anti-acne treatment by Azadirachta indica and Ocimum gratissimum. World Journal of Advanced Research and Reviews, 2024, 22(2), 165-174. Article DOI: https://doi.org/10.30574/wjarr.2024.22.2.1268

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