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eISSN: 2581-9615 || CODEN: WJARAI || Impact Factor 8.2 ||  CrossRef DOI

Research and review articles are invited for publication in March 2026 (Volume 29, Issue 3) Submit manuscript

Tetrahydrocarbazoles as potential therapeutic agents: A review of their synthesis and biological activities

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  • Tetrahydrocarbazoles as potential therapeutic agents: A review of their synthesis and biological activities

Sibaji Sarkar *, Shubham Makvana, Disha Hirani, Isha Makadia, Khyati Dholariya, Harsh Dhokia and Nency Vanpariya

Department of Pharmaceutical Chemistry, Noble University, Bhesan Road, Bamangam, Junagadh, Gujarat, India, Pin: 362001
 
Review Article
World Journal of Advanced Research and Reviews, 2024, 21(03), 2127-2135
Article DOI: 10.30574/wjarr.2024.21.3.0935
DOI url: https://doi.org/10.30574/wjarr.2024.21.3.0935
 
Received on 14 February 2024; revised on 24 March 2024; accepted on 27 March 2024
 
Tetrahydrocarbazoles (THCs) are a remarkable class of compounds characterized by a privileged structural scaffold centered around the natural indole moiety. This extraordinary framework appears in a multitude of naturally occurring pharmacological compounds and alkaloids, demonstrating significant inhibitory activities such as antibacterial effects, protein kinase inhibition, and tumor growth suppression. Given its versatile biological properties, THC consistently the attention of the scientific community.The primary objective of this review is to create a comprehensive reference on the synthesis and biological properties of THCs. In simpler terms, we aim to provide a detailed assessment of various catalysts, including their reaction conditions , synthesis and biological activity This review targets a broad audience interested in understanding the fascinating world of tetrahydrocarbazoles and their impact on medicine and biology .
 
Tetrahydrocarbazole (THcz);substituted 1,2,3,4-Tetrahydrocarbazole ;Structure ;Compound; Biological and Pharmacological Activity; Synthesis
 
https://wjarr.com/sites/default/files/fulltext_pdf/WJARR-2024-0935.pdf

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Sibaji Sarkar, Shubham Makvana, Disha Hirani, Isha Makadia, Khyati Dholariya, Harsh Dhokia and Nency Vanpariya. Tetrahydrocarbazoles as potential therapeutic agents: A review of their synthesis and biological activities. World Journal of Advanced Research and Reviews, 2024, 21(3), 2127-2135. Article DOI: https://doi.org/10.30574/wjarr.2024.21.3.0935

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