In vitro anti-urolithic activity of Chandraprabavathi – A herbo-mineral formulation
College of Pharmacy, MTPG & RIHS, Pondicherry 605 006, India.
Research Article
World Journal of Advanced Research and Reviews, 2019, 03(03), 038–040.
Article DOI: 10.30574/wjarr.2019.3.3.0067
Publication history:
Received on 21 September 2019; revised on 17 October 2019; accepted on 22 October 2019
Abstract:
Chandraprbhavati (CPV) is an Ayurvedic formulation clinically used in the management of urinary calculi. The present study was undertaken to investigate the in-vitro antiurolithic activity of CPV by artificial urine and nucleation assay. Cystone demonstrated better percentage inhibition of calcium oxalate crystals formation than CPV in nucleation assay, however CPV exhibited more inhibition of super saturation of calcium oxalate crystals in artificial urine assay than cystone. The percentage inhibition of calcium oxalate crystals formation increased in dose dependent manner for both the drugs. Thus our study demonstrates primary evidence for CPV possessing antiurolithiatic property in vitro.
Keywords:
Chandraprabhavati; Anti-urolithic; Renal stones
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Copyright © 2019 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0