Bilateral renal agenesis/hypoplasia associated with oligohydramnios and major intrauterine growth restriction: Prenatal ultrasound study

Dinu-Florin Albu 1, Cristina-Crenguța Albu 2, * and Ştefan-Dimitrie Albu 2

1 “Panait Sîrbu” Hospital, 5 Giuleşti Street, 6th District, 060251, Bucharest, Romania.
2 “Carol Davila” University of Medicine and Pharmacy, 37 Dionisie Lupu Street, 1st District, 020021, Bucharest, Romania.
 
Research Article
World Journal of Advanced Research and Reviews, 2022, 16(02), 851-857
Article DOI: 10.30574/wjarr.2022.16.2.1266
 
Publication history: 
Received on 14 October 2022; revised on 20 November 2022; accepted on 23 November 2022
 
Abstract: 
Bilateral renal agenesis/hypoplasia/dysplasia is a lethal malformation in humans with an incidence of 1.3 per 10,000 live births. In the etiology of bilateral renal agenesis/hypoplasia/dysplasia, the genetic factor plays an important role. In addition to genetic factors, the etiology of bilateral renal agenesis/hypoplasia/dysplasia also involves the teratogenic effect of hyperglycemia on the embryo in mothers with insulin-dependent maternal diabetes.
The purpose of this paper is to present a special case of bilateral renal agenesis/hypoplasia/dysplasia, which was successfully diagnosed prenatally by ultrasonography, confirmed and managed appropriately, so as to limit the incidence of serious, lethal congenital malformations.
 
Keywords: 
Renal agenesis; Renal hypoplasia; Prenatal diagnosis; Ultrasound; Congenital malformation
 
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