1 Department of Pharmacy, Shri Sambhaji College of Pharmacy, Khadkut, Nanded, Maharashtra, India, Pin code- 431605
2 Department of Chemistry, Anjuman College of Engineering and Technology, Nagpur, India.
3 Vishveshwarya Group of Institution GB Nagar Ghaziabad Bulandshahr GT Road Phase II Dadri Greater Noida Uttar Pradesh -203207, India.
4 Department of Botany, S.S. Jain Subodh P.G. College (Autonomous), Jaipur-302004, Rajasthan, India.
5 Department of Botany, Sri Venkataramana Swamy College, Vidyagiri, Bantwal-574211, Dakshina Kannada, Karnataka, India.
6 Department of Pharmacy, Rameshwaram Institute of Technology and Management, Sitapur Rd, opposite AKTU campus, Govind Puram Lucknow, Uttar Pradesh 227202, India.
7 Department of Pharmacy, Integrated Academy of Management and Technology Ghaziabad, U.P. – 201009, India.
8 Department of Biochemistry, Jamia Hamdard University, New Delhi, Delhi 110062, India.
Research Article
World Journal of Advanced Research and Reviews, 2024, 21(01), 2720-2728
Received on 18 December 2023; revised on 16 January 2024; accepted on 27 January 2024
To this day, pancreatic cancer remains not only one of the deadliest but also one of the most challenging types of the disease to successfully treat. Innovative therapy approaches are necessary if they are to be utilised in order to improve patient outcomes. The formulation and characterization of solid lipid nanoparticles (SLNs), which are intended for the targeted therapy of pancreatic cancer, are the primary objectives of this research. The solid lipid nanoparticles include an extract from Camptotheca acuminata, which has the possible ability to act as a natural anticancer drug. The goal of this research project is to enhance the therapeutic efficacy of an extract derived from Camptotheca acuminata by concentrating on the development of SLNs as a technique for the administration of drugs. SLNs have improved drug solubility, a longer period in circulation, and higher cellular absorption.
Solid Lipid Nanoparticles; Pancrea; Cancer; Camptotheca acuminata; Formulation
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Sachin Harshavardhan Bhaware, Tasneem K. H. Khan, Shweta Sharma, Shazia M. Jamal, Vinayaka K. S, Ashutosh Kumar, Harjeet Singh and Saniya. Formulation and characterization of solid lipid nanoparticles containing Camptotheca acuminata extract for the treatment of pancreatic cancer. World Journal of Advanced Research and Reviews, 2024, 21(1), 2720-2728. Article DOI: https://doi.org/10.30574/wjarr.2024.21.1.0350