1 Independent Researcher, Nebraska, USA.
2 Independent Researcher, Lima, Ohio, USA.
3 Jiann-Ping Hsu College of Public Health, Georgia Southern University, USA.
4 Independent Researcher, Louisiana, USA.
5 Institute of Human Virology, Nigeria.
6 Department of Community Health and Primary Care, University of Lagos. Nigeria.
7 Abia State University Teaching Hospital, Aba. (ABSUTH), Nigeria.
Review Article
World Journal of Advanced Research and Reviews, 2024, 21(01), 335-351
Received on 22 November 2023; revised on 01 January 2024; accepted on 03 January 2024
This study provides a comprehensive review of the role of bioinformatics in personalized medicine, particularly focusing on its integration with genomics and the consequent revolution in healthcare delivery. The primary objective was to explore how bioinformatics facilitates the transition from traditional healthcare practices to more personalized, predictive, and patient-centered medical treatments. Utilizing a systematic literature review and content analysis, the study examined peer-reviewed articles, conference proceedings, and reports from key databases like PubMed, Web of Science, and Scopus, focusing on publications from 2010 to 2023. Key findings highlight the significant advancements in genomic sequencing technologies and their application in personalized therapeutics. The integration of bioinformatics tools in healthcare systems has shown a substantial impact on patient care, emphasizing the importance of ethical and economic considerations, data privacy, and security. The study also revealed the crucial role of collaborations and partnerships within the industry and healthcare systems for the advancement of personalized medicine. The future landscape of genomic medicine presents both opportunities and challenges, particularly in disease prediction, prevention, and treatment. The study concludes with strategic recommendations for healthcare practitioners and policymakers, emphasizing the need for continuous education, robust policy frameworks, and equitable access to personalized medicine. Future research directions include the development of advanced bioinformatics tools, exploration of ethical implications, and understanding barriers to clinical integration. This study underscores the transformative potential of bioinformatics in revolutionizing healthcare delivery and patient care.
Bioinformatics; Personalized Medicine; Genomic Sequencing; Healthcare Delivery
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Tolulope O Olorunsogo, Obe Destiny Balogun, Oluwatoyin Ayo-Farai, Oluwatosin Ogundairo, Chinedu Paschal Maduka, Chiamaka Chinaemelum Okongwu and Chinyere Onwumere. Bioinformatics and personalized medicine in the U.S.: A comprehensive review: Scrutinizing the advancements in genomics and their potential to revolutionize healthcare delivery. World Journal of Advanced Research and Reviews, 2024, 21(1), 335-351. Article DOI: https://doi.org/10.30574/wjarr.2024.21.1.0016