1 Department of Oral Biology, Faculty of Dental Medicine, Airlangga University, Surabaya 60132 – Indonesia.
2 Faculty of Dental Medicine, Airlangga University, Surabaya 60132 – Indonesia.
3 Department of Oral and Dental Medicine, Faculty of Medicine, Taiz University, Taiz, Yemen.
4 Faculty of Oral and Dental Medicine, Al-Saeed University, Taiz, Yemen.
Review Article
World Journal of Advanced Research and Reviews, 2023, 20(03), 1587-1591
Received on 12 November 2023; revised on 21 December 2023; accepted on 23 December 2023
Introduction: Periodontal disease or disorders can arise from disruption of homeostasis in the periodontal tissue. Ninety percent of people worldwide suffer from periodontal disease, making it the most common dental disease. Periodontitis may increase the rate of mortality and morbidity significantly. Prevention strategies can be carried out with alternative materials. The use of Tithonia diversifolia or insulin leaves has been practiced folklorically by different ethnic groups without scientific evidence, especially for the treatment of conditions related with pain and inflammation.
Methods: The search of literature is conducted through PubMed, Cochrane, the Web of Science, and Google Scholar using keywords for the role of insulin leaf extract (Tithonia diversifolia) as anti-inflammatory and antibacterial for periodontitis. Journal published at least five years ago is acquired. The journal covered the topics of various risk factors for Varicella. The criteria for this study are national and international accredited journals by Scopus and non-Scopus.
Results: Of the 15 articles reviewed, it is known that there is a role for insulin leaf extract (Tithonia diversifolia) in the treatment and prevention of periodontitis.
Conclusion: From the literature review article obtained, there are several roles of insulin leaf extract (Tithonia diversifolia) in the treatment and prevention of periodontitis with anti-inflammatory and antibacterial mechanisms. Using insulin leaves as mouthrinse can also improve oral health and reduce tooth decay.
Tithonia diversifolia; Periodontitis; Anti-inflammatory; Antibacterial
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Indeswati Diyatri, Rini Devijanti, Tantiana, Dealtrini Pongsumae, Muhammad Afif Wardana, Mohammed Ahmed Aljunaid and Huda Rashad Qaid. Anti-inflammatory and antibacterial properties of insulin leaves (Tithonia diversifolia) for Periodontitis. World Journal of Advanced Research and Reviews, 2023, 20(3), 1587-1591. Article DOI: https://doi.org/10.30574/wjarr.2023.20.3.2599