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eISSN: 2582-8185 || CODEN: WJARAI || Impact Factor 8.2 ||  CrossRef DOI

Research and review articles are invited for publication in March 2026 (Volume 29, Issue 3) Submit manuscript

Carbetocin (PABAL) and postpartum hemorrhage (PPH)

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  • Carbetocin (PABAL) and postpartum hemorrhage (PPH)

Fouad Ech chouyekh 1, *, Badr El Marjani 2, Sofia Jayi 1, FZ Fdili Alaoui 1, Hikmat Chaara 1 and M.A Melhouf 1

1 Department of Obstetrics Gynecology II, CHU Hassan II, Sidi Mohamed Ben Abdellah University, Fez, Morocco.
2 Faculty of Letters and Human Sciences-Dhar El Mahraz-Sidi Mohamed Ben Abdellah University, Fez, Morocco.
 
Research Article
World Journal of Advanced Research and Reviews, 2023, 19(03), 428–438
Article DOI: 10.30574/wjarr.2023.19.3.1811
DOI url: https://doi.org/10.30574/wjarr.2023.19.3.1811
 
Received on 30 July 2023; revised on 07 September 2023; accepted on 09 September 2023
 
Objective: with the marketing in our country of the Carbetocin molecule for the prevention of postpartum hemorrhage which currently relies on the administration of Oxytocin, we tried to make a comparison of the effectiveness between the 2 products.
Method: review of the literature and studies made by comparing the 2 products.
Results: Carbetocin has been proposed in the prevention of uterine atony during Cesarean: Carbetocin (Pabal) is a synthetic analog of human oxytocin: its longer duration of action (approximately 5 hours instead of 1 hour 30 minutes for Syntocinon), and single dose make it a molecule of choice in the therapeutic strategy prevention of uterine atony.
Reliable and well-tolerated Carbetocin appears to be as effective as Oxytocin in clinical practice in preventing PPH.
 
Carbetocin; Oxytocin; Uterine atony; Cesarean; Preventing PPH; Postpartum hemorrhage
 
https://wjarr.com/sites/default/files/fulltext_pdf/WJARR-2023-1811.pdf

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Fouad Ech chouyekh, Badr El Marjani, Sofia Jayi, FZ Fdili Alaoui, Hikmat Chaara and M.A Melhouf. Carbetocin (PABAL) and postpartum hemorrhage (PPH). World Journal of Advanced Research and Reviews, 2023, 19(3), 428-438. Article DOI: https://doi.org/10.30574/wjarr.2023.19.3.1811

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