Parathyroid hormone-related protein and primary teeth eruption in stunting children

Sindy Cornelia Nelwan, Udijanto Tedjosasongko *, Ardianti Maartrina Dewi and Puspita Ayuningtyas

Department of Pediatric Dentistry, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
 
Review Article
World Journal of Advanced Research and Reviews, 2022, 14(03), 016–021
Article DOI: 10.30574/wjarr.2022.14.3.0492
 
Publication history: 
Received on 25 April 2022; revised on 31 May 2022; accepted on 02 June 2022
 
Abstract: 
Stunting is a linear growth failure as an indicator of malnutrition status which is identified by comparing the height of children with normal height according to the same age and sex. Children are categorized as stunting if the child`s height is shorter than the average height of the same age and sex and has a standard deviation of below minus 2 according to the standard who. The cause of stunting is multifactorial, including disruption of hormone function, one of which is a parathyroid hormone. Parathyroid Hormone-related Protein (PTHrP) plays a role in the tooth-eruption process. This literature review aims to study the role of PTHrP on the eruption rate of primary teeth in stunting children. Malfunction of the parathyroid glands in stunted children can cause a deficiency of PTHrP levels. PTHrP and vitamin D play a role in the maintenance and affect calcium levels. Deficiency levels of PTHrP and vitamin d can lead to decreased absorption of calcium in the blood. Calcium deficiency in children can cause osteoclasts and osteoblasts to decrease, which can affect bone growth and tooth eruption patterns.  In stunting children, the level of PTHrP will decrease so that tooth eruption will be inhibited.
 
Keywords: 
Good Health and Well - Being; Stunting; Parathyroid Hormone-Related Protein; Tooth Eruption
 
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