Acute fatty liver of pregnancy About 20 cases

H Ouasif; A qaba; H ouadiaa; A soummani; S Sayagh

doi:10.30574/wjarr.2023.18.1.0638

eISSN: 2581-9615 || CODEN: WJARAI || Impact Factor 8.2 || CrossRef DOI

Research and review articles are invited for publication in April 2026 (Volume 30, Issue 1) Submit manuscript

Acute fatty liver of pregnancy About 20 cases

H Ouasif ^{1, *}, A qaba ², H ouadiaa ², A soummani ²and S Sayagh ¹

¹ Hematology Laboratory, Mohamed IV university hospital, Marrakech Morocco.

² Department of obstetrics and gynecology, Mohamed IV university hospital, Marrakech Morocco.

Research Article

World Journal of Advanced Research and Reviews, 2023, 18(01), 923-930

Article DOI: 10.30574/wjarr.2023.18.1.0638

DOI url: https://doi.org/10.30574/wjarr.2023.18.1.0638

Publication history

Received on 04 March 2023; revised on 19 April 2023; accepted on 21 April 2023

Abstract

Our retrospective study concerned acute hepatic steatosis in pregnancy: diagnostic problems, severity and therapeutic perspectives in the Moroccan context.

It concerns a series of 20 cases of SHAG collected in the department of gynecology-obstetrics and maternal resuscitation of the CHU MOHAMED VI in Marrakech over a 5-year period from January 2017 to December 2021.

We included in this sample women admitted during pregnancy or post partum for management of SHAG.

In our series, the frequency of SHAG was 1 case per 4340 deliveries.

The age of the patients ranged from 18 to 45 years, with an average of 28 years and an average gestational age of 32 days and 3 weeks. Thus the majority of patients were multiparous and multigestational with a frequency of 55%.

Clinically: polyuria-polydipsia syndrome was present in 20% of patients, nausea-vomiting in 70% and epigastralgia in 60%.

Biologically: Hypoglycaemia present in 60%, hyperleukocytosis in 85%, creatinine level above 12mg/l in 70%, hyperuricaemia in 75%, hepatic cytolysis in 90%, hyper bilirubinaemia in 95% with conjugated predominance, prolonged PT in 50% and hyperammonia in 10%.

Concerning complications, acute fulminant liver failure was observed in 30% of our patients, it is the most serious and fatal complication.

The therapeutic management of SHAG requires, in addition to uterine evacuation associated with adequate medical and surgical resuscitation.

Keywords

Hepatic steatosis; Pregnancy; Balance; Obstetrics; Thrombocytopenia

Download Article PDF

https://wjarr.com/sites/default/files/fulltext_pdf/WJARR-2023-0638.pdf

Preview Article PDF

How to cite this article

H Ouasif, A qaba, H ouadiaa, A soummani and S Sayagh. Acute fatty liver of pregnancy About 20 cases. World Journal of Advanced Research and Reviews, 2023, 18(1), 923-930. Article DOI: https://doi.org/10.30574/wjarr.2023.18.1.0638

Copyright © Author(s). All rights reserved. This article is published under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits use, sharing, adaptation, distribution, and reproduction in any medium or format, as long as appropriate credit is given to the original author(s) and source, a link to the license is provided, and any changes made are indicated.

All statements, opinions, and data contained in this publication are solely those of the individual author(s) and contributor(s). The journal, editors, reviewers, and publisher disclaim any responsibility or liability for the content, including accuracy, completeness, or any consequences arising from its use.

Developed & Designed by VS Infosolution

Acute fatty liver of pregnancy About 20 cases

H Ouasif ^{1, *}, A qaba ², H ouadiaa ², A soummani ²and S Sayagh ¹

Preview Article PDF

Get Certificates

Issue details

Acute fatty liver of pregnancy About 20 cases

H Ouasif 1, *, A qaba 2, H ouadiaa 2, A soummani 2 and S Sayagh 1

Preview Article PDF

Get Certificates

Issue details

H Ouasif ^{1, *}, A qaba ², H ouadiaa ², A soummani ²and S Sayagh ¹