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eISSN: 2581-9615 || CODEN: WJARAI || Impact Factor 8.2 ||  CrossRef DOI

Research and review articles are invited for publication in March 2026 (Volume 29, Issue 3) Submit manuscript

Rare association of Kallman Morsier syndrome with a non-functioning pituitary microadenoma

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  • Rare association of Kallman Morsier syndrome with a non-functioning pituitary microadenoma

F. Mennani *, S. Bammou, S. Rafi, G. El Mghari and N. El Ansari

Department of Endocrinology, Diabetology, Metabolic Diseases Nutrition CHU Mohamed VI, Marrakech, Morocco.
 
Case Study
World Journal of Advanced Research and Reviews, 2023, 18(01), 217-219
Article DOI: 10.30574/wjarr.2023.18.1.0556
DOI url: https://doi.org/10.30574/wjarr.2023.18.1.0556

 

Received on 25 February 2023; revised on 04 April 2023; accepted on 07 April 2023
 
Kallmann's syndrome (KS) is a form of hypogonadotropic hypogonadism associated with a defect in the sense of smell, due to abnormal migration of gonadotropin-releasing hormone-producing neurons. We report the case of a patient aged 16 years and 6 months who presented a micropenis with poor development of secondary sexual characteristics and anosmia. Plasma levels of luteinizing hormone, follicle stimulating hormone and testosterone were very low, while chromosomal analysis showed a 46XY karyotype. Hypothalamic-pituitary MRI showed bilateral agenesis of the olfactory bulbs associated with a 4 mm pituitary microadenoma. The patient was put on hormone replacement therapy with a good response. 
 
Hypogonadotropic hypogonadism; Kallmann's syndrome; Micropenis; Anosmia
 
https://wjarr.com/sites/default/files/fulltext_pdf/WJARR-2023-0556.pdf

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F. Mennani, S. Bammou, S. Rafi, G. El Mghari and N. El Ansari. Rare association of Kallman Morsier syndrome with a non-functioning pituitary microadenoma. World Journal of Advanced Research and Reviews, 2023, 18(1), 217-219. Article DOI: https://doi.org/10.30574/wjarr.2023.18.1.0556

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