Home
World Journal of Advanced Research and Reviews
International Journal with High Impact Factor for fast publication of Research and Review articles

Main navigation

  • Home
    • Journal Information
    • Editorial Board Members
    • Reviewer Panel
    • Abstracting and Indexing
    • Journal Policies
    • Our CrossMark Policy
    • Publication Ethics
    • Issue in Progress
    • Current Issue
    • Past Issues
    • Instructions for Authors
    • Article processing fee
    • Track Manuscript Status
    • Get Publication Certificate
    • Join Editorial Board
    • Join Reviewer Panel
  • Contact us
  • Downloads

eISSN: 2581-9615 || CODEN: WJARAI || Impact Factor 8.2 ||  CrossRef DOI

Research and review articles are invited for publication in April 2026 (Volume 30, Issue 1) Submit manuscript

Review: Quorum sensing mechanism between Streptococcus mutans and Candida albicans in the pathogenesis of dental caries

Breadcrumb

  • Home
  • Review: Quorum sensing mechanism between Streptococcus mutans and Candida albicans in the pathogenesis of dental caries

Indah Listiana Kriswandini 1, * and Rashif Almas 2

1 Department of Oral Biology, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
2 Dental Medicine Education Study Program, Faculty of Dental Medicine, Universitas Airlangga, Surabaya-Indonesia.
 
Review Article
World Journal of Advanced Research and Reviews, 2023, 17(01), 1079-1082
Article DOI: 10.30574/wjarr.2023.17.1.0066
DOI url: https://doi.org/10.30574/wjarr.2023.17.1.0066
 
Received on 13 December 2022; revised on 24 January 2023; accepted on 26 January 2023
 
Background: Dental caries is one of the most common oral diseases that affects all age groups worldwide. Caries is a slow progressing chronic disease characterized by localized tooth decay. Caries arises from interactions on the tooth surface between microorganisms, microorganism products, host (saliva) and diet (sugar), which leads to the formation of pathogenic biofilms, or dental plaque, and causes tooth decay. Streptococcus mutans (S. mutans) bacteria are the main microorganisms that play a role in causing dental caries. The results of several clinical studies indicate that, apart from S. mutans, the fungus Candida albicans (C. albicans) is often detected in high numbers in caries. The existence of these two species in one biofilm allows the two species to communicate between cells which is called quorum sensing.
Objective: To determine the Quorum sensing mechanism between S. mutans and C. albicans in the development of the pathogenesis of caries.
Methods: 3 databases namely PUBMED, Web of Science and Scopus, were used to search for articles according to predetermined inclusion and exclusion criteria.
Results: quorum sensing between S. mutans and C. albicans in the same biofilm can change gene expression in both species of microorganisms, as well as increase the growth of both species of microorganisms.
Conclusion: Symbiosis between S. mutans and C. albicans in the oral cavity is very detrimental to humans because it can exacerbate the buildup of acid which results in caries.
 
Streptococcus mutans; Candida albicans; Quorum sensing; Caries; Biofilm
 
https://wjarr.com/sites/default/files/fulltext_pdf/WJARR-2023-0066.pdf

Preview Article PDF

Indah Listiana Kriswandini and Rashif Almas. Review: Quorum sensing mechanism between Streptococcus mutans and Candida albicans in the pathogenesis of dental caries. World Journal of Advanced Research and Reviews, 2023, 17(1), 1079-1082. Article DOI: https://doi.org/10.30574/wjarr.2023.17.1.0066

Copyright © Author(s). All rights reserved. This article is published under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits use, sharing, adaptation, distribution, and reproduction in any medium or format, as long as appropriate credit is given to the original author(s) and source, a link to the license is provided, and any changes made are indicated.

All statements, opinions, and data contained in this publication are solely those of the individual author(s) and contributor(s). The journal, editors, reviewers, and publisher disclaim any responsibility or liability for the content, including accuracy, completeness, or any consequences arising from its use.

Get Certificates

Get Publication Certificate

Download LoA

Check Corssref DOI details

Issue details

Issue Cover Page

Editorial Board

Table of content

Copyright © 2026 World Journal of Advanced Research and Reviews - All rights reserved

Developed & Designed by VS Infosolution