1 Department of Clinical Immunology, Hirosaki University School of Health Sciences, 66-1 Honcho, Hirosaki 036-8565, Japan.
2 Joint Department of Veterinary Clinical Medicine, Faculty of Agriculture, Tottori University. 4-101 Koyama-Minami, Tottori 680-8553, Japan.
3 NEO CIRCLE Co., Ltd, 4-8-6 Akasaka Minatoku, Tokyo 107-0052, Japan.
4 FUJICLEANTECH Co., Ltd. 1-1-40 Aoyagi, Aomori 038-0004, Japan.
Research Article
World Journal of Advanced Research and Reviews, 2022, 15(02), 186-190
Article DOI: 10.30574/wjarr.2022.15.2.0788
Received on 29 June 2022; revised on 06 August 2022; accepted on 08 August 2022
The Carcite type of Corbicula japonica shell powder developed at high temperature 500℃ had improved mal-function of liver in the LEC rat liver disorder model, and restored its function. Additional a new bio-function of the fired shell powder was lately found to lower the blood sugar level in the Type 2 diabetes model mouse (KK/TaJcl). These mice were raised with 2.5% shell powder for a month showed the significant lower level of blood sugar at 81±23mg to that of the control raised without shell powder at 208±86mg (P = .05). Fat globlues deposition and vacuoles formation in the liver were clearly less in the shell powder-fed group compared to those of the control group in histo-pathological inspections. Anti-diabetes efficiency of the Carcite type shell powder prepared at 500℃ 2hrs treatment acquired a blood sugar reduction ability suggesting applicability against the human diabetes patients.
Multi-functional calcium; Corbicula japonica calcite; Diabetes; Blood sugar level improvement; Type 2 diabetes mouse model
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Jin-Ichi Sasaki, Yoshiharu Okamoto, Tetsuei Someya and Yoshinori Minegishi. High temperature manufactured Corbicula japonoca shell powder (Carcite type crystal structure) improved diabetes in mouse. World Journal of Advanced Research and Reviews, 2022, 15(2), 186-190. Article DOI: https://doi.org/10.30574/wjarr.2022.15.2.0788