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eISSN: 2582-8185 || CODEN: WJARAI || Impact Factor 8.2 ||  CrossRef DOI

Research and review articles are invited for publication in March 2026 (Volume 29, Issue 3) Submit manuscript

An overview on synthesis and biological activity of pyrimidines

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  • An overview on synthesis and biological activity of pyrimidines

Mosaad Sayed Mohamed, Samir Mohamed Awad, Neama Abdallah Abd El-tawab * and Naglaa Mohamed Ahmed

Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Helwan University, Ain Helwan, Helwan, Egypt.
 
Review Article
World Journal of Advanced Research and Reviews, 2022, 15(01), 272–296
Article DOI: 10.30574/wjarr.2022.15.1.0689
DOI url: https://doi.org/10.30574/wjarr.2022.15.1.0689
 
Received on 05 June 2022; revised on 09 July 2022; accepted on 11 July 2022
 
Pyrimidines represent an important class of heterocycles containing two nitrogen atoms at position 1 and 3 of the six membered ring show wide range of biological activities. Numerous methods for the synthesis of pyrimidine and their diverse reactions offer enormous scope in the field of medicinal chemistry. Pyrimidine possesses wide spectrum of biological activities including antitubercular, antibacterial, antifungal, antiviral, anti-inflammatory, antimalarial, anticancer, and anti-HIV activity. The present review attempts to give brief information about the synthesis and various biological activities of pyrimidines and their derivatives.
 
Pyrimidine; pyrimidine derivatives; Synthesis; Biological activities
 
https://wjarr.com/sites/default/files/fulltext_pdf/WJARR-2022-0689.pdf

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Mosaad Sayed Mohamed, Samir Mohamed Awad, Neama Abdallah Abd El-tawab and Naglaa Mohamed Ahmed. An overview on synthesis and biological activity of pyrimidines. World Journal of Advanced Research and Reviews, 2022, 15(1), 272-296. Article DOI: https://doi.org/10.30574/wjarr.2022.15.1.0689

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