Organizing Pneumonia Revealing Mixed Connective Tissue Disease: A Case Report

Organizing pneumonia is a pulmonary condition characterized by inflammation of the alveoli and the development of connective tissue in the lungs. It can be triggered by infections, autoimmune diseases, or medications. Mixed connective tissue disease, on the other hand, is an autoimmune disorder that combines features of several diseases, such as lupus and Sjögren's syndrome.

This case report describes a 24-year-old female patient, initially misdiagnosed with pleuropulmonary tuberculosis after presenting with respiratory symptoms and general signs. Failure of antituberculous treatment led to a re-evaluation of the diagnosis, ultimately revealing organizing pneumonia related to mixed connective tissue disease. Immunological testing and salivary gland biopsy confirmed the diagnosis of mixed connective tissue disease, including systemic lupus erythematosus and Sjögren's syndrome. The patient was treated with corticosteroids and immunosuppressive agents, with significant clinical improvement, highlighting the diagnostic challenges and the importance of a multidisciplinary approach.