Fatal alliance: Aspergillosis and bronchial Adenocarcinoma: A case report

Pathological coexistence in pulmonary diseases poses significant diagnostic and therapeutic challenges, especially when fungal infections overlap with malignant neoplasms. Aspergilloma, an opportunistic infection caused by Aspergillus spp., typically develops in pre-existing pulmonary cavities, while bronchial adenocarcinoma represents one of the most aggressive forms of lung cancer. The coexistence of these two conditions is rare but can greatly complicate clinical management and diagnosis. Here, we present a unique case of aspergilloma associated with advanced bronchial adenocarcinoma in a patient with superior vena cava syndrome (SVCS) and a history of chronic smoking.