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eISSN: 2581-9615 || CODEN: WJARAI || Impact Factor 8.2 ||  CrossRef DOI

Research and review articles are invited for publication in March 2026 (Volume 29, Issue 3) Submit manuscript

Apeced's syndrome and lichen planus, is there a causal link? Clinical case and review of the literature (Case report)

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  • Apeced's syndrome and lichen planus, is there a causal link? Clinical case and review of the literature (Case report)

Imane Moustaghit 1, Ikram Damoune 2 and Abdelmajid Chraibi 2

1 Department of Endocrinology, CHU Souss Massa Agadir, Faculty of Medicine, University Ibn Zohr 80000 Agadir, Morocco.

2 Faculty of Medicine, Agadir University ibn Zohr, 80000 Agadir, Morocco.

Case Report

World Journal of Advanced Research and Reviews, 2025, 28(01), 1775-1779

Article DOI: 10.30574/wjarr.2025.28.1.3553

DOI url: https://doi.org/10.30574/wjarr.2025.28.1.3553

Received on 09 September 2025; revised on 22 October 2025; accepted on 25 October 2025

  • Background: Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy syndrome (APECED) is an autosomal recessive disorder characterised by the combination of autoimmune endocrine damage, mucocutaneous candidiasis and ectodermal tissue damage.
  • Case presentation: we report the case of an 18-year-old female patient with APECED syndrome: the abnormalities found are in chronological order: primary hypoparathyroidism, mucocutaneous candidiasis, Addison's disease, Lichen planus, Biermer's anemia and autoimmune ovaritis. Lichen planus was diagnosed clinically and histologically.
  • Conclusion: The occurrence of lichen planus is unusual in this syndrome. In this review, we first review the current knowledge of APECED syndrome and focus on the relationship between APECED syndrome and Lichen planus.

APECED Syndrome; Lichen Planus; Genetics

https://wjarr.com/sites/default/files/fulltext_pdf/WJARR-2025-3553.pdf

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Imane Moustaghit, Ikram Damoune and Abdelmajid Chraibi. Apeced's syndrome and lichen planus, is there a causal link? Clinical case and review of the literature (Case report). World Journal of Advanced Research and Reviews, 2025, 28(1), 1775-1779. Article DOI: https://doi.org/10.30574/wjarr.2025.28.1.3553

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