Toxic optic neuropathy due to methanol: About two cases

Hajar MOURABITI 1, 2, *, Sahar AMRANI HANCHI 1, 2, Hasnae HOUMMANI 1, 2 and Sanae ACHOUR 1, 2

1 Department of toxico-pharmacology, CHU HASSAN II, Fez, Morocco.
2 Biomedical and transrational research laboratory, Faculty of Medicine and Pharmacy. Sidi Mohamed Ben Abdallah University. Fez, Morocco.
 
Research Article
World Journal of Advanced Research and Reviews, 2024, 22(02), 2094–2098
Article DOI: 10.30574/wjarr.2024.22.2.1580
 
Publication history: 
Received on 12 April 2024; revised on 25 May 2024; accepted on 28 May 2024
 
Abstract: 
Ingesting methanol voluntarily or accidentally can result in irreversible optic neuropathy or death. This report discusses two patients admitted to the Hassan II University Hospital Center in Fes after methanol intoxication. Both patients experienced gastrointestinal and neurological symptoms, including severe metabolic acidosis. Despite undergoing treatments like hemodialysis, they suffered permanent visual impairment. While methanol-induced optic neuropathy is less frequent nowadays, complete recovery without long-term effects has only been observed in cases of mild poisoning and early treatment. This study emphasizes the importance of early diagnosis and tailored treatment to minimize the severe consequences of methanol poisoning.
 
Keywords: 
Methanol; Intoxication; Sequelae; Optic neuropathy; Diagnosis
 
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