Theoretical consideration of solubility by Hildebrand solubility approach

Vaibhav Gulabrao Bhamare 1, *, Renuka Ravindra Joshi 2, Mayur Sakharam Gangurde 3 and Vijay V Pawar 3

1 KKWES College of Pharmacy, Panchavati, Nashik, Maharashtra.
2 MGV’s Institute of Pharmacy, Malegaon Camp Tal: Malegaon Dist: Nashik, Maharashtra.
3 SVS Institute of Pharmacy, Mungase, Tal: Malegaon Dist: Nashik, Maharashtra
 
Review Article
World Journal of Advanced Research and Reviews, 2021, 12(03), 528–541
Article DOI: 10.30574/wjarr.2021.12.3.0680
 
Publication history: 
Received on 03 November 2021; revised on 12 December 2021; accepted on 14 December 2021
 
Abstract: 
Pharmaceutical field is widely focusing on solubility parameter models to select solvent or non-solvent that can enhance solvency of drug. Solubility Parameter is very useful concept in understanding the mechanism of solvent and solvency behavior with their applications in pharmaceuticals to open the door of research having focus on theoretical considerations of solubility. Hildebrand and Hansen Solubility Parameter are frequently used to identify solvents.
 
Keywords: 
Solubility; Solvation; Hildebrand Solubility Parameter; Hansen solubility parameter
 
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