Synergistic antibacterial activity of Murraya koenigii and Cynodon dactylon against pathogenic strains

Patil Rupali Bhushan 1, *, Chavan Pranita Sandip 1 and Desai Deepa Mahendra 2

1 Department of Pharmacognosy, N.S.S. College of Pharmacy, Maharashtra State Board of Technical Education, Mumbai, India.
2 Department of Pharmaceutical Chemistry, N.S.S. College of Pharmacy, Maharashtra State Board of Technical Education, Mumbai, India.
 
Research Article
World Journal of Advanced Research and Reviews, 2020, 05(03), 124-128
Article DOI: 10.30574/wjarr.2020.5.3.0063
 
Publication history: 
Received on 07 March 2020; revised on 24 March 2020; accepted on 25 March 2020
 
Abstract: 
The present   study     deals   with   the   synergistic   antibacterial   activity   of   Cynodon   dactylon   and Murraya   koenigii.  Combined concentration of the drugs extracts was tested   against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Bacillus subtilis by agar well diffusion technique. The results of antibacterial activity revealed that the aq. extracts of Cynodon dactylon exhibited maximum to moderate inhibitory activity against all test pathogens. Maximum antibacterial activity by aqueous extract of Cynodon dactylon were exhibited against Escherichia coli, Staphylococcus aureus followed by Bacillus subtilis and Pseudomonas aeruginosa whereas aqueous extract of Murraya koenigii showed moderate sensitivity on all pathogens. Combined concentration of both drugs showed good antibacterial activity against all four pathogens.
 
Keywords: 
Antibacterial activity; Cynodon dactylon; Murraya koenigii; Agar well diffusion technique
 
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