Study on association of possible link of ions and insulin resistance in hypertension and diabetes mellitus
1 Department of Medical Laboratory Science, Niger Delta University, Nigeria.
2 Department of Biochemistry, University of Lagos, Nigeria.
Research Article
World Journal of Advanced Research and Reviews, 2022, 14(02), 402–405
Article DOI: 10.30574/wjarr.2022.14.2.0443
Publication history:
Received on 10 April 2022; revised on 15 May 2022; accepted on 18 May 2022\
Abstract:
To authenticate doubts relating to influence of altered state of some ions in insulin resistance and hypertension we analysed some biomolecules; glucose, insulin, glycated hemoglobin, magnesium, zinc, sodium, potassium and copper from diabetics, non-diabetics and hypertensives. Adopting spectroscopic and immunoassay methods values obtained were statistically evaluated by Anova (Analysis of variance). We observed identical pattern in glucose concentration, glycated hemoglobin and insulin levels among hypertensive and non-hypertensive subjects. However, an aggregated insulin response to glucose was elevated significantly (34.5+3.2 vs 20+2.3 µIU/mL, P<0.05). Zinc and magnesium levels were inversely correlated with HbAIc in insulin dependent diabetics and Non-insulin dependent diabetic (P<0.05). We observed Values increasing in tandem relationship with hypertension. We conclude that while hypertension and insulin resistance may have differential biochemical precursor, a nexus could be established for the place of ionic interferences in these disorders.
Keywords:
Ions; Insulin Resistance; Hypertension Diabetes mellitus
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