Standardization of Kandankathiriyaadhy Kyazham: A Classical Siddha Drug

R. Saradhadevi *, G. Essakky Pandian and A. Kingsly

Department of Gunapadam, Government Siddha Medical College, Palayamkottai, Tirunelveli, Tamil-Nadu, India.
 
Research Article
World Journal of Advanced Research and Reviews, 2024, 21(01), 2622–2635
Article DOI: 10.30574/wjarr.2024.21.1.0339
 
Publication history: 
Received on 14 December 2023; revised on 26 January 2024; accepted on 28 January 2024
 
Abstract: 
Kandankathiriyaadhy Kyazham is one of the polyherbal formulation mentioned in siddha system of medicine. The main objective of the study was to evaluate the quality of formulation Kandankathiriyaadhy Kyazham by conducting Physicochemical, Phytochemical evaluation through advanced analytical techniques. The organoleptic nature of the drug provides the purity and quality of the formulation. The results obtained from physicochemical evaluation shows that the total ash value of Kandankathiriyaadhy Kyazham was “2.8±0.3%”, in which the acid insoluble ash was “0.041±0.008%”, loss on drying at 105ºC of the formulation Kandankathiriyaadhy Kyazham was noted to be “7.4±0.88” in which water soluble extract value and alcohol soluble extract value was “20.2±1.53 and 8.333=1.15% “respectively. High performance Thin Layer Chromatography analysis of reveals the appearance Kandankathiriyaadhy Kyazham of ten prominent peaks corresponds to presence of ten versatile phyto components present with in it.Rf value of the peaks ranges from “0.13 to 0.91”. Phyto chemical analysis of Kandankathiriyaadhy Kyazham reveals the emergence of phytocomponents like Alkaloids, Flavonoids, Steroids, Triterpenoids, Coumarin, Phenol, Tannin, Protein, Saponins, Sugar, Betacyanin. In conclusion, the polyherbal formulation of Kandankathiriyaadhy Kyazham possess significant phytocomponents and have beneficial effects towards treating various disorders.
 
Keywords: 
Standardization; Decoction; Physicochemical; Kandankathiriyaadhy Kyazham; Polyherbal.
 
Full text article in PDF: 
Share this